Name | AflatoxinG2 |
Synonyms | AF G2 AflatoxinG2 AFLATOXIN G2(RG) 10a-hexahydro-5-methoxy-1(7ar-cis)- |
CAS | 7241-98-7 |
EINECS | 230-643-4 |
Molecular Formula | C17H14O7 |
Molar Mass | 330.29 |
Density | 1.3099 (rough estimate) |
Melting Point | 237-240 °C |
Boling Point | 387.74°C (rough estimate) |
Specific Rotation(α) | D -473° (c = 0.084 in chloroform) |
Flash Point | 2 °C |
Water Solubility | 15mg/L(temperature not stated) |
Solubility | DMSO or Methanol |
Appearance | Shape white to yellow powder. blue-green fluorescence. |
BRN | 1692017 |
Storage Condition | 2-8°C |
Sensitive | Sensitive to light |
Refractive Index | 1.4790 (estimate) |
MDL | MFCD00078141 |
Physical and Chemical Properties | Bioactive Aflatoxin G2 is a major naturally occurring aflatoxin. Aflatoxin G2 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus. The order of toxicity was Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2. |
Risk Codes | R45 - May cause cancer R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. R36 - Irritating to the eyes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R65 - Harmful: May cause lung damage if swallowed R48/23/24/25 - R36/38 - Irritating to eyes and skin. R46 - May cause heritable genetic damage |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S16 - Keep away from sources of ignition. S7 - Keep container tightly closed. S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. |
UN IDs | UN 3462 6.1/PG 1 |
WGK Germany | 3 |
RTECS | LV1700000 |
HS Code | 30029090 |
Hazard Class | 6.1(a) |
Packing Group | I |
Toxicity | LD50 orally in day old duckling: 172.5 mg/50 gm body wt (Carnaghan) |
Reference Show more | 1. [IF=10.618] Feng Hong et al."Highly sensitive magnetic relaxation sensing method for aflatoxin B1 detection based on Au NP-assisted triple self-assembly cascade signal amplification."Biosens Bioelectron. 2021 Nov;192:113489 2. [IF=9.038] Junpeng Zhao et al."Horseradish peroxidase-catalyzed formation of polydopamine for ultra-sensitive magnetic relaxation sensing of aflatoxin B1."J Hazard Mater. 2021 Jun;:126403 |
specific rotation | D -473° (c = 0.084 in chloroform) |
EPA chemical information | Aflatoxin G2 (7241-98-7) |
product description
Aflatoxin is a toxic metabolite of Aspergillus flavus and Aspergillus parasiticus. It is a kind of compound with basic structure containing difuran ring and coumarin (oxonaphtho ketones). Twelve kinds have been isolated and identified. Aflatoxin is easily soluble in chloroform and methanol but insoluble in n-hexane, petroleum ether and ether. Fluorescence is generated under long-wave ultraviolet light, which is named B1,B2,G1,G2,M1,M2,P1,R1,GM and toxic alcohol according to different fluorescence colors, RF values and structures. Among them, B1 has the highest yield, the greatest toxicity and the strongest carcinogenicity. Aflatoxin is heat-resistant and can only be cracked at 280 ℃, so there is little damage at general cooking temperature. It is very stable in neutral and weak acidic solution, slightly decomposed in acidic solution with pH1 ~ 3, and rapidly decomposed and destroyed in solution with pH9 ~ 10. In 1961, it was discovered that peanut cakes contaminated by Aspergillus flavus can induce liver cancer in rats. In 1962, aflatoxin was identified and proved to be a strong carcinogen. Aflatoxin with double bonds at the end of difuran ring in the structure is easy to form epoxidation metabolites and enhance its toxicity, carcinogenicity and mutagenicity. Aflatoxin mainly pollutes grain and oil and its products, such as peanuts, peanut oil, corn, rice and cottonseed. Aflatoxin B1 is used as the pollution index in domestic food testing, which can be detected by thin layer chromatography and high pressure liquid phase method.
category
Toxic substances
Toxicity classification
Highly toxic
Acute toxicity
oral-duck LD50:2.45 mg/kg
flammability hazard characteristics
Flammable; burning releases stimulating smoke
storage and transportation features
The warehouse is ventilated and dry at low temperature; stored separately from food ingredients
Fire extinguishing agent
Dry powder, foam, sand, carbon dioxide, mist water
toxic substance data | 7241-98-7(Hazardous Substances Data) |